Description

SS‑31 (Elamipretide, Bendavia)

Description

• SS‑31 (also known as elamipretide or Bendavia) is a cell‑penetrating tetrapeptide that selectively targets and stabilizes cardiolipin in the inner mitochondrial membrane.
• Investigational mitochondrial‑targeted peptide studied for preserving mitochondrial function, reducing oxidative stress, and improving cellular bioenergetics.

Key benefits (research findings)

• Helps stabilize mitochondrial membranes and preserve electron transport chain efficiency in preclinical and clinical studies.
• Reduces mitochondrial reactive oxygen species (ROS) production and associated oxidative damage.
• May improve cellular ATP production and protect tissues from ischemia‑reperfusion and metabolic stress in experimental models.
• Studied for potential benefits in cardiomyopathy, mitochondrial myopathies, age‑related decline in mitochondrial function, and ischemia/reperfusion injury.

Primary uses

• Preclinical and clinical research investigating mitochondrial protection, metabolic resilience, and therapies for mitochondrial or ischemic conditions.
• Tool compound in translational studies evaluating mitochondrial‑targeted therapeutics.

Suggested use

• Administer only per validated research protocols or clinical trial dosing regimens. Common routes in studies include intravenous or subcutaneous administration; dosing and schedules are indication‑specific.
• Follow institutional, sponsor, and regulatory guidance for formulation, dosing, and monitoring.

Safety and storage

• Safety profile is investigational and context‑dependent; reported adverse events in trials vary by dose and population—monitoring is required.
• Avoid unsupervised human use. Handle and dispose of per institutional chemical and biologic safety protocols.
• Store per manufacturer or protocol instructions (commonly refrigerated and protected from light); maintain sterility for injectable formulations and adhere to expiration guidance.

Quick facts

• Mechanism: mitochondrial membrane (cardiolipin) targeting to reduce oxidative damage and support bioenergetics.
• Status: investigational with ongoing preclinical and clinical research; regulatory approvals vary by region and indication.
• Not a substitute for established medical treatments—use only within approved research or clinical frameworks.

Research Use Only Disclaimer

Products sold by SoCo Peptides are intended strictly for laboratory research purposes only.

These compounds are not intended for human consumption, veterinary use, household use, cosmetic use, or therapeutic application. They are not drugs, foods, or dietary supplements and have not been evaluated or approved by the FDA.

By purchasing from this website, the customer represents that they are a qualified researcher or laboratory professional and understand the risks associated with handling research materials.

All products must be handled by trained professionals in appropriate research facilities and in accordance with all applicable laws and regulations.

SoCo Peptides makes no guarantees or claims regarding safety, effectiveness, or medical benefit.